Differentiation and validation of human iPSC-derived atrial cardiomyocytes

Poster Description

There is a growing trend for utilisation of native human cells in drug discovery to overcome common translational disconnects between in vitro screening data, preclinical animal models, and clinical trials in man. Translational assays using cardiomyocytes derived from human induced pluripotent stem cells (hiPSC) are increasingly appreciated as an accessible cell source for cardiac disease modelling, drug screening, and safety pharmacology.

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Development of a High-Throughput Automated Electrophysiology Assay for Human NaV1.9 Inhibitor Screening

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Development and Evaluation of Novel Solution Pairs to Enhance Seal Resistance in Automated Patch Clamp Experiments

Metrion and Sophion present findings that determine whether other insoluble salts can act as seal enhancers and how these solution pairs affect the biophysical properties and pharmacology of the investigated ion channels.

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Metrion Biosciences is a contract research organisation (CRO) specialising in high-quality preclinical drug discovery services.
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