Alex Haworth, Senior Scientist at Metrion, introduces a poster demonstrating Metrion's development of a monoclonal CHO cell line expressing hNav1.9, validated via manual and automated patch clamp techniques.

Introduction to ion channel screening at Metrion

Introduction to neuroscience at Metrion

Leaders in ion channel, cardiac safety and neuroscience screening

Enhance the predictive accuracy of cardiac safety assessments to ensure safer drug development and reduce the likelihood of late-stage failures due to cardiac toxicity

In this video we demonstrate how to perform the lysosomal patch clamp technique to study ion channels on the lysosomal membrane.

This webinar presents data on sensory neuron ion channels, sensory neuron excitability and mechanism underlying trigeminal neuralgia.

Robust high-throughput automated electrophysiology assay using a monoclonal CHO-hNav1.9 cellular reagent suitable for fully supporting a Nav1.9 discovery program.

We have developed a robust high-throughput automated electrophysiology assay using a monoclonal CHO-hNav1.9 cellular reagent suitable for fully supporting a Nav1.9 discovery program.

To overcome seal enhancer limitations, Sophion and Metrion collaborated to determine whether other insoluble salts can act as seal enhancers and how these solution pairs affect the biophysical properties and pharmacology of the investigated ion channels.