NS5806, widely used as a Kv4-selective activator, also activates TREK-1 and TREK-2 potassium channels.
1 Wolfson Centre for Age-Related Diseases, Guy's Campus, King's College London, London, United Kingdom
2 Metrion Biosciences Ltd, Building 2 Granta Centre, Granta Park, Cambridge, United Kingdom
3 Imperial College London, Pain Research Group, Chelsea and Westminster Hospital, London, United Kingdom
4 Research Group Neuroscience of the Interdisziplinary Center for Clinical Research, University Hospital of the RWTH Aachen, Aachen, Germany
5 Institute for Physiology, University Hospital of the RWTH Aachen, Aachen, Germany
(2023) PAIN
10.1097/j.pain.0000000000003115
Spontaneous activity in peripheral sensory nerves: a systematic review
NS5806, widely used as a Kv4-selective activator, also activates TREK-1 and TREK-2 potassium channels.
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