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Seal enhancers on the Qube 384: An alternative to F

Metrion and Sophion collaborated to determine whether other insoluble salts can act as seal enhancers, or whether this property is unique to CaF2.

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What is the Comprehensive In Vitro Proarrhythmia Assay (CiPA) initiative?

CiPA logoThe International Council on Harmonization (ICH) S7B and E14 regulatory guidelines were introduced in 2005 to evaluate the proarrhythmic liability of new drugs.

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Webinar recording - Accelerating Pain Therapeutic Discovery: Nav1.9 as a Drug Target for Treatment of Pain

Academic case study on Nav1.9 as a drug target by Associate Professor David Bulmer (University of Cambridge). Overview of Metrion’s newly developed Nav1.9 screening assays by Metrion CSO, Dr. Eddy Stevens.

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Development of a High-Throughput Automated Electrophysiology Assay for Human Nav1.9 Inhibitor Screening

Alex Haworth, Senior Scientist at Metrion, introduces a poster demonstrating Metrion's development of a monoclonal CHO cell line expressing hNav1.9, validated via manual and automated patch clamp techniques.

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Introduction to ion channel screening at Metrion

Introduction to ion channel screening at Metrion

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Introduction to neuroscience at Metrion

Introduction to neuroscience at Metrion

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Introduction to Metrion, leaders in ion channel, cardiac safety and neuroscience screening

Leaders in ion channel, cardiac safety and neuroscience screening

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Rapidly define potential QTc and QRS risk

Enhance the predictive accuracy of cardiac safety assessments to ensure safer drug development and reduce the likelihood of late-stage failures due to cardiac toxicity

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Studying ion channels on the lysosomal membrane

In this video we demonstrate how to perform the lysosomal patch clamp technique to study ion channels on the lysosomal membrane.

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Breaking New Ground in Chronic Pain Relief: Advancements in Drug Discovery for Trigeminal Neuralgia

This webinar presents data on sensory neuron ion channels, sensory neuron excitability and mechanism underlying trigeminal neuralgia.

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Metrion Biosciences is a contract research organisation (CRO) specialising in high-quality preclinical drug discovery services.
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