Metrion Biosciences’ laboratory at Granta Park, Cambridge.

A Dedicated and Flexible Service

Our approach provides a dedicated, flexible service tailored to each customer’s requirements. It is supported by rapid reporting and data interpretation by our experienced ion channel team.

We provide a range of exceptional ion channel electrophysiology expertise and services. These services include high-quality, cost-effective compound screening assays, detailed characterisation of lead compounds in human cells and native tissue, as well as confirmation of efficacy in stem cell and other phenotypic models.

Our Services

Metrion Biosciences is a specialist pre-clinical Contract Research Organisation (CRO) focused on delivering a range of high-quality ion channel drug discovery services. We provide highly skilled electrophysiology screening services to support customer medicinal chemistry optimisation programmes, CiPA-compliant cardiac safety profiling assays, neuroscience assays and translational assays.

We Provide:

High quality ion channel electrophysiology expertise and services
High quality, cost-effective compound screening assays
Detailed characterisation of lead compounds in human cells and native tissue
Confirmation of efficacy in stem cell and other phenotypic models
Rapid reporting and data interpretation by our experienced ion channel team
A dedicated, flexible service tailored to each customer’s requirements

Our Facilities

Metrion is located within the Cambridge bio cluster, one of Europe’s largest bioscience research hubs. Our state of the art laboratories at Granta Park house high-quality facilities for native and engineered cell line and induced pluripotent stem cell culture, a comprehensive suite of automated patch clamp platforms, multiple manual patch clamp rigs, fluorescence-based screening capabilities and laboratory data management and reporting systems.
Metrion Biosciences’ laboratory at Granta Park, Cambridge.

Ion channel screening: high-quality platforms

Ion channel drug discovery is reliant on sophisticated screening platforms. Metrion scientists have decades of accumulated experience utilising such devices. We offer flexible support for assay development, primary target screening, hit confirmation, lead optimisation and SAR, mechanistic and phenotypic studies.

All of our electrophysiology platforms deliver high-quality recordings and data and include:
Qube-384
QPatch II-48
QPatch-48
FLIPR-Penta
Patchliner
Manual patch clamp
Multi-Electrode Array and impedance (native and iPSC neurons and cardiomyocytes)
FlexStation
Metrion Biosciences

Let’s work together

If you have any questions or would like to discuss your specific assay requirements, we will put you directly in touch with a member of our scientific team. Contact us today to discover more.
Contact us for a quote or discussion
Metrion Biosciences is a contract research organisation (CRO) specialising in high-quality preclinical drug discovery services.
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