Cell line generation
Ready-to-go and customised cell lines
Metrion has an extensive catalogue of ready-to-go ion channel cell lines for ion channel screening, high-throughput screening, cardiac safety screening and/or neuroscience projects. Metrion can also generate custom cell lines, including complex multi-subunit cell lines to meet the specific requirements of customer projects.
Metrion scientists have over 30 year’s of combined experience in molecular biology and stable cell line generation for high-throughput screening and compound profiling. Clients trust these scientists to develop robust cell lines, giving consistent, reproducible, and biologically relevant data, which significantly enhances the efficiency, reliability, and success rate of identifying new therapeutic agents.
Investing in the generation of high-quality cell lines reduces costs over time by reducing the need for repeat experiments and minimizing the risk of failed drug candidates due to unreliable data.
Our approach
By following processes meticulously, Metrion ensures that cell lines are biologically relevant and consistently deliver advanced and relevant insights into human diseases and potential therapies:
- Custom made expression constructs for optimal expression in the cell line of choice
- Identify individual cell clones using limited dilution or fluorescence-activated cell sorting
- Functional assessment of individual clones across multiple screening platforms to identify the most appropriate and reliable clone
- Expansion and banking of stocks for future screening campaigns
Outsourcing to Metrion
Speed up the identification and development of new therapeutics and enable your team to focus on other critical research projects, by outsourcing to our highly experienced cell line generation scientists.