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Gain-of-function mutations in Nav1.6 and epileptic seizures

Watch on demand the Metrion Biosciences webinar presented by Manoj K. Patel, Ph.D, Associate Professor at the University of Virginia where he speaks about “Gain-of-function mutations in Nav1.6 and epileptic seizures“.

The webinar took place on Thursday 29th November 2022 at 16:00 EDT.

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Metrion Biosciences – Laboratory tour

Metrion Biosciences is a specialist ion channel contract research organisation providing drug discovery services to pharmaceutical and bioscience customers worldwide. Discover more about our capabilities and facilities in this short introductory video.

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Metrion Webinar – Dr. Kris Kahlig

Dr. Kris Kahlig is the Head of Biology at Praxis Precision Medicines Inc. a clinical stage biopharmaceutical company translating genetic insights into the development of therapies for patients affected by CNS disorders. Kris presented at the Metrion Webinar series on “Using Dynamic Action Potential Clamp Modelling of Nav1.2 Variants to Support the Prediction of Clinical Phenotype in DEE”.

The webinar took place on Thursday 5th May 2022 at 16:00 BST.

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Metrion Webinar – Dr. Greg Carr

We are delighted to present the fourth speaker in our “Ion Channels in Drug Discovery” webinar series – Dr. Greg Carr from the Lieber Institute for Brain Development. Greg’s presentation was entitled: “A role for hERG potassium channels in cognitive function”

The webinar took place on Thursday 3rd February 2022 at 16:00 BST.

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Metrion Webinar – Professor David Sheppard

We are delighted to present the third speaker in our webinar series – Professor David Sheppard from the University of Bristol. David’s presentation was focused on Cystic Fibrosis and his talk was “Cystic Fibrosis: Rescuing Faulty Channels with Targeted Therapies”.

The webinar took place on Tuesday 30th November 2021 at 16:00 BST.

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Metrion Webinar – Professor Stephen Tucker

We are delighted to present the second speaker in our webinar series – Professor Stephen Tucker from the Department of Physics at the University of Oxford. Stephen speaking on the topic of the TASK-1 K2P channel and his talk will be entitled “Defective X-gating caused by de novo mutations in the TASK-1 K2P channel (KCNK3) underlies a developmental disorder with sleep apnea”.

The webinar took place on Thursday 16th September 2021 at 16:00 BST.

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An overview of Metrion Biosciences

Metrion Biosciences’ CEO Dr Andrew Southan presents an overview of Metrion Biosciences, highlighting the company’s vision, expertise and services. December 10th, 2020.

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Designing multiple assay protocols for ligand-gated ion channels using the stacked-tip feature on the Patchliner and SP384i platforms

Marc Rogers (Metrion CSO) presents a talk at the Nanion Virtual User Meeting 2020 entitled “Designing multiple assay protocols for ligand-gated ion channels using the stacked-tip feature on the Patchliner and SP384i platforms”. 14th October 2020.

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Validation and optimization of automated patch-clamp voltage-gated Ca2+ channel assays

Marc Rogers (Metrion CSO) takes part in a collaborative webinar with Nanion Technologies entitled “Validation and optimization of automated patch-clamp voltage-gated Ca2+ channel assays”.

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The benefits of targeting ion channels for pain and some of the hurdles in developing successful ion channel modulators

As part of the the LabTube meets series of interviews Marc Rogers, Metrion Biosciences CSO, outlines the benefits of targeting ion channels for pain and some of the hurdles in developing successful ion channel modulators.

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Metrion Biosciences is a contract research organisation (CRO) specialising in high-quality preclinical drug discovery services.
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