Why choose Metrion as your CRO?

Metrion is your premier partner for ion channel screening. We are also specialists in cardiac safety and neuroscience research.

Our combination of specialist expertise, advanced technology, flexibility, and proven reliability makes us an ideal choice for pharmaceutical and bioscience companies seeking high-quality preclinical drug discovery and safety services.

Industry-leading expertise in ion channel drug discovery

With over 250 years combined experience in ion channel electrophysiology, we have the expertise and skillset to offer clear strategic insights that are critical for successful drug discovery. We have a detailed understanding of both voltage- and ligand-gated ion channels, plus extensive experience of configuring high quality assays for multimodal and leak channels. Our experience guarantees high-quality, accurate data to drive your medicinal chemistry strategy.

Tailored and flexible services

Our services and assay formats are highly adaptable to the specific needs of each customer. This flexibility is complemented by rapid data reporting, allowing for efficient progression of drug discovery projects.

Comprehensive screening capabilities

We excel in offering cost-effective compound screening assays and detailed characterisation of lead compounds in human cells and native tissues. This expertise also extends to confirming compound efficacy in stem cell-derived and other phenotypic models.

Proven track record

Our leadership team have been key decision makers in multiple successful drug discovery programs, and Metrion’s laboratory team has proven ability to deliver high-quality data on time and within budget. This experience and reliability is essential for maintaining momentum in drug discovery projects.

State-of-the-art technology

Metrion is a leader in automated patch clamp technology, with team members who pioneered 384-well APC screening, we have a first-class track record of operating a range of gigaseal APC platforms. This technology allows for high-throughput, precise screening, which is crucial for modern drug discovery efforts.

Dedicated and experienced team

All Metrion colleagues are dedicated to providing a personalised service, ensuring that customers’ specific needs and timelines are met with precision and professionalism.

  • As another happy customer, I can add that I recently got data from Metrion scientists for manual electrophysiology testing of compounds against a native cell current. The data look fantastic and reproduced the recombinant cell potency. I gave them no information about the compounds, and they noted that one was a state-dependent blocker, showed example traces, and reported IC50s for peak current inhibition and area under the trace. They are also very careful in how they solubilize, dilute and store the samples.

    Top pharma

    USA
  • We are very encouraged by the data and appreciate the detailed description of the analysis. These discussions are very useful to the team and highlight the complexities of these experiments in terms of execution and interpretation.

    Drug Discovery and Development Company

    USA
  • Attention to detail with executing the study and the quality of reports is the best we have ever seen. By far the most accurate and well interpreted data. Explanations clear for a non-expert to understand.

    BIOTECH

    USA
  • We recognize this type of study is very difficult and the cells we provided posed technical challenges. We also appreciate the timeliness of the study execution and the detailed report you provided.

    TOP 10 PHARMA

    GLOBAL
  • We appreciate the thoroughness, clearness of explanation and results, and the work done above and beyond to troubleshoot.

    BIOPHARMACEUTICAL COMPANY

    USA
  • Brilliant – both response time to my email and turnaround time for compounds!

    BIOTECH

    Germany
  • Thanks as usual for the excellent data.

    Charity

    UK
  • This data is excellent which gives me confidence for your assays. I look forward to working with you on more studies.

    large pharma

    USA
  • Really good data showing exactly what we would expect for a [target] inhibitor; we know how difficult these recordings are to perform.

    Large Pharmaceutical Company

    UK
  • Many thanks for the data today. The graphs look great.

    UK Mid-sized Pharma

    UK
Metrion Biosciences is a contract research organisation (CRO) specialising in high-quality preclinical drug discovery services.
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