Serving the worldwide pharmaceutical and life sciences industry

Metrion Biosciences’ laboratory at Granta Park, Cambridge.

We are leaders in providing high-quality ion channel screening, cardiac safety screening and GLP hERG testing, and neuroscience services to the worldwide pharmaceutical and life sciences industry. With customers in more than 20 countries and on five continents, we deliver efficient and successful ion channel screening expertise to meet our customers’ needs promptly and accurately.

Our customers range from large pharmaceutical companies and established entities within the life sciences industry to smaller specialist businesses looking to validate, develop or de-risk ion channel modulators as they progress towards a nomination for clinical development. We also work with charities, academics and start-ups to explore the potential of particular compounds using pre-validated industry-leading assays for ion channels.

Why partner with Metrion?

Ion channel drug discovery is reliant on sophisticated screening platforms. Metrion scientists have decades of accumulated experience utilising such devices.

All of our electrophysiology platforms deliver high-quality recordings and data. Our platforms offer flexible support for assay development, primary target screening, hit confirmation, lead optimisation and SAR, mechanistic and phenotypic studies.
Exceptional ion channel electrophysiology expertise and services
High quality, cost-effective compound screening assays
Detailed characterisation of lead compounds in human cells and native tissue
Confirmation of efficacy in stem cell and other phenotypic models
Rapid reporting and data interpretation by our experienced customer focused team
A dedicated, flexible service tailored to each customer’s requirements
  • As another happy customer, I can add that I recently got data from Metrion scientists for manual electrophysiology testing of compounds against a native cell current. The data look fantastic and reproduced the recombinant cell potency. I gave them no information about the compounds, and they noted that one was a state-dependent blocker, showed example traces, and reported IC50s for peak current inhibition and area under the trace. They are also very careful in how they solubilize, dilute and store the samples.

    Top pharma

    USA
  • We are very encouraged by the data and appreciate the detailed description of the analysis. These discussions are very useful to the team and highlight the complexities of these experiments in terms of execution and interpretation.

    Drug Discovery and Development Company

    USA
  • Attention to detail with executing the study and the quality of reports is the best we have ever seen. By far the most accurate and well interpreted data. Explanations clear for a non-expert to understand.

    BIOTECH

    USA
  • We recognize this type of study is very difficult and the cells we provided posed technical challenges. We also appreciate the timeliness of the study execution and the detailed report you provided.

    TOP 10 PHARMA

    GLOBAL
  • We appreciate the thoroughness, clearness of explanation and results, and the work done above and beyond to troubleshoot.

    BIOPHARMACEUTICAL COMPANY

    USA
  • Brilliant – both response time to my email and turnaround time for compounds!

    BIOTECH

    Germany
  • Thanks as usual for the excellent data.

    Charity

    UK
  • This data is excellent which gives me confidence for your assays. I look forward to working with you on more studies.

    large pharma

    USA
  • Really good data showing exactly what we would expect for a [target] inhibitor; we know how difficult these recordings are to perform.

    Large Pharmaceutical Company

    UK
  • Many thanks for the data today. The graphs look great.

    UK Mid-sized Pharma

    UK
Metrion Biosciences

Let’s work together

If you have any questions or would like to discuss your specific assay requirements, we will put you directly in touch with a member of our scientific team. Contact us today to discover more.
Contact us for a quote or discussion
Metrion Biosciences is a contract research organisation (CRO) specialising in high-quality preclinical drug discovery services.
Copyright © 2024 Metrion. All rights reserved | Privacy notice | Registered as a company in England and Wales: 09669815 | VAT: GB 219828479
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