By Molly Rowlett, Industrial Placement Student, Metrion Biosciences
My 12 month industrial placement at Metrion Biosciences was a truly remarkable experience that has helped me grow both personally and professionally. Choosing to complete a placement year was a big decision for me which was made 100% worth it!
I worked alongside many specialist scientists to understanding the principles of ion channel drug discovery and learning the specific disciplines involved. My main focus over the year was my project: The development and validation of patch-clamp assays to study large conductance calcium-activation potassium (BK) channels.
Additionally, I was lucky enough to work on a variety of ion channels, including IK(KCa3.1), NaV1.5, CaV3.2, KvLQT and TRPML1 using patch-clamp technique, and had the opportunity to present the poster ‘Development of TRPML1-4A assays across manual, automated patch-clamp, and fluorescence-based platforms’ at a scientific conference.
Overall, this industrial placement has been a valuable and inspiring experience which will benefit me in my final year at the University of Bristol and beyond. I am extremely grateful to the entire Metrion team for welcoming me so quickly and supporting me along the way.
![Industrial placement review: Molly Rowlett 1 Molly Rowlett presenting poster 'Development of TRPML1-4A assays across manual, automated patch-clamp, and fluorescence-based platforms' at Cambridge Ion Channel Forum.](https://www.metrionbiosciences.com/wp-content/uploads/2024/07/Molly-poster.jpg)
patch-clamp, and fluorescence-based platforms‘ at Cambridge Ion Channel Forum.
![Industrial placement review: Molly Rowlett 2 Molly Rowlett leaving cake](https://www.metrionbiosciences.com/wp-content/uploads/2024/07/Molly-leaving-cake-1-779x1024.jpg)
![Industrial placement review: Molly Rowlett 3 IMG 2311 scaled](https://www.metrionbiosciences.com/wp-content/uploads/2024/07/IMG_2311-scaled.jpeg)