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A clinically translatable hiPSC cardiomyocyte model to predict QTc and QRS cardiac risk

Presented at the SPS meeting in September 2024, Dr Steve Jenkinson presents Metrion’s human induced pluripotent stem cell (hiPSC)-derived cardiomyocyte assay, an advanced tool, providing key advantages, for early cardiac derisking in drug discovery.

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Validation of an impedance-based phenotypic screening assay able to detect multiple mechanisms of chronic cardiotoxicity in human stem cell-derived cardiomyocytes

Presentation by Marc Rogers, CSO Metrion Biosciences, Nanion technologies Exhibitor session, 2020 Biophysical Society meeting, San Diego USA.

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M-type K+ channels in nociceptive pathways: physiological roles and therapeutic potential

Presentation from Metrion Biosciences’ external speaker series, Professor Nikita Gamper, University of Leeds, 5th February 2019.

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Utility of human iPSC-derived CMs for preclinical safety assays and disease modelling

This talk was presented by Dr Sarah Williams at the Axol Metrion Interactive Stem Cell Forum held in May 2018. This project received funding from the Eurostars-2 joint program with co-funding from the European Union Horizon 2020 Research and Innovation Program.

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Therapeutic potential of activators of two-pore domain ion channels

Presentation from Metrion Biosciences’ external speaker series, Professor Alistair Mathie, Medway School of Pharmacy, 13th October 2017.

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In depth profiling of human iPSC cardiomyocytes: From electrophysiology to phenotypic assays

In depth profiling of human iPSC cardiomyocytes: From electrophysiology to phenotypic assays. Metrion’s Saïd El Haou presentation covers the topics of Manual Patch Clamp – Current Clamp, Axion Maestro – MEA and the Nanion CardioExcyte96 – Impedance.

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Modulation of voltage-gated calcium channels in disease

Presentation from the Metrion Biosciences’ external speaker series, Professor Gary Stephens, University of Reading, 28th November 2016.

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Metrion Biosciences is a contract research organisation (CRO) specialising in high-quality preclinical drug discovery services.
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