Design a customised hit-finding campaign that complements your ion channel strategic requirements

Access to high quality compound libraries enables greater flexibility and increases diversity and enables us to maximise customer R&D budgets even more effectively.

The combination of our specialist ion channel expertise with substantial high-throughput screening (HTS) and hit-finding experience gives customers access to a dedicated team of drug discovery scientists, ensuring the correct strategic choices are made in compounds selected for screening. We also provide a Structured Data File (SDF) of all libraries to compare against existing libraries, further increasing efficiency.

Enamine have the world’s largest compound collection, including CNS and ion channel focused target libraries. Specifically, the Hit Locator Library (HLL) contains 460,000 compounds which we can split into screening sets, giving customers the benefit of cost efficiencies in the number of compounds screened. In addition, analog-by-catalog from Enamine in-stock and make-on-demand REAL libraries presents a fast and efficient way for hit expansion and SAR studies. Read the press release.

Assay.Works combine non-redundant small molecule sets as modular high-throughput screening decks. Access to 150,000 small molecule compounds optimized for lead-likeness and diversity, free of undesirable chemotypes, verified by LC/UV/MS.

FLIPR® Penta: traditional fluorescence-based technique.

Qube 384: next-generation HTS electrophysiology for a direct read of ion channel function.

Metrion Biosciences

If you have any questions or would like to discuss your specific assay requirements, we will put you directly in touch with a member of our scientific team. Contact us today to discover more.